Technische = Universit�t Braunschweig

   Institute= f�r Informatik

    

Einladung zum


Bioinformatik-Kolloquium

    

   Zeit:

   Donnerstag, 02.12.04, 14:00 Uhr

   Ort:

   M�hlenpfordtstr= . 23, = IZ

   H�rsaal M 161, 1. OG

    

    

    

    

   Vortragender:

   Christian von Mering

    = 

   Euro= p�isches Molekularbiologie Labor Heidelberg<= span
   lang=EN-GB    style='font-size:16.0pt;mso-bidi-font-size:12.0pt;color:navy;
   mso-ansi-language:EN-GB'>

    

    

   Thema:

   Functional protein = networks: interaction data mining and application
   to environmental = genomics

    

    

    

    

    

   Zusammenfassung:

    


   The majority of proteins perform their = biological role not in
   isolation, but in close functional interaction with other proteins.
   For a systems-level understanding of cellular processes, a = complete
   and accurate inventory of protein-protein interactions is essential.
   Unfortunately, current experimental data on protein-protein    associations are incomplete, scattered over various model organisms,
   and often = error-prone. I will present a data-mining system dedicated
   to the collection, = validation and integration of protein interaction
   data � including associations = predicted solely in silico. 
   In the second part of my talk, I will = describe how this consolidated
   interaction data is useful for making sense of an = exciting new
   source of data: environmental genomics data. This type of data    provides, for the first time, an unbiased view of microbial
   communities, and we = find sets of interacting genes with marked
   preferences for certain = environments � helping us to understand
   how environmental requirements shape genome = content.




    

    

   Die Dozenten der = Informatik<= /b>